Profile, screen, identify and quantify a wide variety of compounds with confidence
Our next generation Thermo Scientific LC-MS systems deliver on ease without sacrificing high performance. A unified instrument architecture enables same performance accessories between systems, facilitates easier method transfer, and accelerates familiarization for new users. Intelligence-driven systems enables the highest quality mass spectrometry data for increased confidence. Pre-defined experimental conditions enables more users to access and succeed. Streamlined data processing software, algorithms and libraries address the most challenging research and routine applications.

Popular LC-MS products


Orbitrap Eclipse Tribrid Mass Spectrometer   LC-MS Medical Devices for In Vitro Diagnostic Use   Orbitrap Exploris Mass Spectrometers
An instrument designed with your most difficult analytical challenges in mind, the Thermo Scientific Orbitrap Eclipse mass spectrometer incorporates the latest inventions in ion transmission and control, extended m/z range, and real-time decision making to expand the breadth of your work and push your science beyond today's discovery. This system is ideally suited for proteomics, structural biology, small-molecule, and biopharmaceutical characterization experiments.   Our family of liquid chromatography mass spectrometry (LC-MS) instruments for in vitro diagnostics provides clinical labs with consistent reliable results, faster. These comprehensive, reliable LC-MS platform solutions offer greater flexibility than immunoassays, facilitate cost savings and enable clinical laboratories to achieve their productivity goals, while ensuring confidence in results of laboratory developed tests (LDTs). These Class I LC-MS medical devices leverage the power of a complete software suite conforming to in vitro diagnostic (IVD) requirements and offering an optional laboratory information system (LIS) connection.   Thermo Scientific Orbitrap Exploris mass spectrometry is quantitative high-resolution, accurate-mass (HRAM) liquid chromatography mass spectrometry (LC-MS) with record-setting performance for your next-generation laboratory. The power of built-in intelligence, sensitivity and selectivity delivers depth of analysis to the lowest levels with high quantitative accuracy and precision. This extraordinary power is now available in an expanded portfolio to meet your exact analytical requirements. Scale up your research and translate your results more rapidly and simply than ever before with Orbitrap Exploris mass spectrometry.

Featured LC-MS categories


Orbitrap LC-MS   Orbitrap Exploris LC-MS   Orbitrap Tribrid LC-MS
Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization and quantitation, and comprehensive sample analysis.   Empowering translational research scientists to more extensively deploy MS for rigorous, high-throughput protein identification, quantitation and structural characterization the Orbitrap Exploris 480 MS combines proven technology, advanced capabilities and an intelligence-driven analytical framework.   Push the limits of detection, characterization and quantitation with Thermo Scientific Orbitrap Tribrid mass spectrometers that enable multiple sophisticated modes of analysis.
Q Exactive Orbitrap LC-MS   Ion Trap LC-MS   Triple Quadrupole LC-MS
Move from compound discovery into targeted quantitation for your sample type by choosing from a broad portfolio of Thermo Scientific Q Exactive Quadrupole-Orbitrap mass spectrometers.   For general purpose mass spectrometers, Ion trap mass spectrometers are cost-effective and can easily be operated by students learning the fundamentals of MS or for analytical applications.   From achieving ultimate sensitivity requirements, robustness, reliability, and speed, triple quadrupole LC-MS systems help you address your challenges in routine, targeted quantitation for all molecule types.
Single Quadrupole LC-MS   LC-MS Medical Devices   LC-MS Software
These economical high-performance MS systems have the capacity to keep up with even the fastest UHPLC applications.   Comprehensive, reliable LC-MS platform solutions that enable clinical laboratories to achieve desired productivity and throughput goals, while ensuring confidence in results in laboratory developed tests (LDTs).   The right complement for our outstanding LC-MS systems, our software offers most comprehensive solution to data acquisition, processing, analysis, and reporting.