Charles River has developed and optimized a range of FDA approved quantitative and qualitative LAL reagent formulations that provides increased sensitivity, greater linearity, and superior interference resistance.

Endosafe® Cartridge Technology   Kinetic Chromogenic LAL   Kinetic Turbidimetric LAL
The Endosafe® cartridge technology is our advanced solution to our customers’ need for higher sensitivity in the LAL test and faster quantitative results. Created to improve and refine our use of LAL, the cartridge technology cuts out a significant amount of the raw material and accessories required for traditional LAL assay methods while reducing time-consuming preparation and technician variability.
A fully quantitative and uniquely stable kinetic chromogenic LAL reagent, Endochrome-K™ includes an enhanced KCA formulation that delivers an unrivaled combination of sensitivity, linearity, and interference resistance.
Charles River’s kinetic turbidimetric (KTA) LAL reagents allow you to improve your testing with a single FDA-licensed product that performs both kinetic and gel-clot analysis with accelerated reaction times and no pre-incubation necessary. Second-generation reagent, KTA2, releases one of the fastest turbidimetric LAL reaction times in the industry, and with the enhanced LAL reagent water formulations deliver an unrivaled combination of sensitivity, linearity, and interference resistance properties with minimal assay times.
Gel-Clot LAL   LAL-Accessories    
The gel-clot LAL test is a basic qualitative method best used for low-volume laboratories. Charles River’s lysate features a firm gel over a wide range of sensitivities as the buffered reagent provides improved interference resistance for routine LAL tests.
Charles River provides all the necessary endotoxin-free test tubes and accessory products required to run an LAL assay. All accessory products are provided with a certificate of quality certifying appropriate endotoxin levels. These high-quality accessories impart control and consistency to LAL assays and the LAL laboratory, thereby minimizing invalid results and repeat testing.